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Istanbul is the largest city in Turkey, constituting the country's economic, cultural, and historical center. With a population of over 15 million, it is home to 18% of the population of Turkey. Istanbul is among the largest cities in Europe and in the world by population. It is a city on two continents; about two-thirds of its population live in Europe and the rest in Asia. Istanbul straddles the Bosphorus – one of the world's busiest waterways – in northwestern Turkey, between the Sea of Marmara and the Black Sea. Its area of 5,461 square kilometers (2,109 mi2) is coterminous with Istanbul Province.

The city now known as Istanbul developed to become one of the most significant cities in history. Byzantium was founded on the Sarayburnu promontory by Greek colonists, potentially in the seventh century BC. Over nearly 16 centuries following its reestablishment as Constantinople in 330 AD, it served as the capital of three empires: the Roman Empire (later known as the Byzantine Empire, 330–1204 and 1261–1453), the Latin Empire (1204–1261), and the Ottoman Empire (1453–1922). It was instrumental in the advancement of Christianity during Roman and Byzantine times, before the Ottomans conquered the city in 1453 and transformed it into an Islamic stronghold and the seat of the last caliphate. Although the Republic of Turkey established its capital in Ankara, palaces and imperial mosques still line Istanbul's hills as visible reminders of the city's previous central role. The historic centre of Istanbul is a UNESCO World Heritage Site